[3-(trifluoromethoxy)phenyl]hydrazine

[3-(trifluoromethoxy)phenyl]hydrazine - Names and Identifiers

Name	(3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE
Synonyms	3-Trifluoromethoxyphenylhydrazine [3-(trifluoromethoxy)phenyl]hydrazine 2-TRIFLUOROMETHYL PHENYLHYDRAZINE HCL 3-trifluoromethoxy phenylhydrazine(HCl) 3-Trifluoromethoxy-phenylhydrazine hydrochloride (3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE [3-(trifluoromethoxy)phenyl]-hydrazine hydrochloride
CAS	133115-55-6
InChI	InChI=1/C7H7F3N2O/c8-7(9,10)13-6-3-1-2-5(4-6)12-11/h1-4,12H,11H2

[3-(trifluoromethoxy)phenyl]hydrazine - Physico-chemical Properties

Molecular Formula	C7H8ClF3N2O
Molar Mass	228.6
Density	1.408g/cm³
Boling Point	226.8°C at 760 mmHg
Flash Point	91°C
Vapor Presure	0.0803mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.526
MDL	MFCD02671043

[3-(trifluoromethoxy)phenyl]hydrazine - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code	29280000

[3-(trifluoromethoxy)phenyl]hydrazine - Introduction

3-Trifluoromethoxyphenylhydrazine (HCl) is an organic compound with the chemical formula C7H5F3N2O. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Trifluoromethoxyphenylhydrazine (HCl) is a colorless to pale yellow solid.
-Melting point: about 65-70°C.
-Thermal stability: relatively stable under conventional experimental conditions.
-Solubility: Soluble in some organic solvents, such as ethanol and acetone.

Use:
-3-Trifluoromethoxyphenylhydrazine (HCl) can be used as a heterocyclic synthesis intermediate, and has a wide range of applications in the fields of medicine, pesticides and dyes.
-It can also be used as a reducing agent and nitrogen source.

Preparation Method:
-3-Trifluoromethoxyphenylhydrazine (HCl) is prepared by a variety of methods, and a common method is obtained by reacting p-trifluoromethylchlorobenzene with phenylhydrazine.
-The specific steps can be summarized as follows:
1. Add trifluoromethylchlorobenzene and phenylhydrazine in the appropriate molar ratio to the reaction vessel.
2. The reaction is carried out in an appropriate solvent, commonly used solvents are dimethylformamide (DMF) or dichloromethane (DCM).
3. The reaction is carried out at an appropriate temperature and time.
4. Filter to obtain the product, if necessary, further purification process can be carried out.

Safety Information:
-3-Trifluoromethoxyphenylhydrazine (HCl) is relatively stable under normal conditions, but it may decompose at high temperatures or in contact with fire sources, producing toxic gases.
-It is an irritating compound that may cause irritation to the skin, eyes and respiratory system.
-Wear appropriate protective gloves, goggles and protective mask during operation.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:51